Natural History of Multiple Sclerosis with Childhood Onset
نویسندگان
چکیده
منابع مشابه
Natural history of multiple sclerosis with childhood onset.
BACKGROUND The course and prognosis of childhood-onset multiple sclerosis have not been well described. METHODS We used data from 13 adult neurology departments affiliated with the European Database for Multiple Sclerosis (EDMUS) network to identify a cohort of 394 patients who had multiple sclerosis with an onset at 16 years of age or younger and a comparison group of 1775 patients who had m...
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S U M M A R Y — A 2 y e a r o l d b o y w a s a d m i t t e d o w i n g t o a s u b a c u t e e p i s o d e o f a t a x i c g a i t a n d h e a r i n g d e f i c i t . C o m p u t e r i z e d t o m o g r a p h y ( C T ) w a s n o r m a l a n d c e r e b r o s p i n a l f l u i d ( C S F ) a n a l y s i s r e v e a l e d g a m m a g l o b u l . n s l e v e l o f 1 5 . 4 % ( n o r m a l 7 t o 1 4...
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c DEFINITION OF NATURAL HISTORY The definition of the natural history of acute illnesses has been diYcult to establish. Imagine, however, the degree of uncertainty in an earlier age when fever itself was considered to be a disease. The appearance of fever could represent a banal upper respiratory disease or underlying untreatable infection or malignancy. Good outcomes oVered unlimited opportuni...
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The natural history of MS is highly variable. There is substantial heterogeneity in the clinical manifestations but, at this point, it is reasonable to consider all idiopathic inflammatory demyelinating diseases of the central nervous system as representing a spectrum of the same disease. In large populations, 20% to 40% have "benign disease," defined as having less than moderate disability aft...
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The North American Research Committee on Multiple Sclerosis (NARCOMS) Registry is a database that contains information from over 35,000 patient volunteers on symptom severity in 11 domains commonly affected in multiple sclerosis (MS): mobility, hand function, vision, fatigue, cognition, bowel/bladder function, sensory, spasticity, pain, depression, and tremor/coordination. The Registry affords ...
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ژورنال
عنوان ژورنال: New England Journal of Medicine
سال: 2007
ISSN: 0028-4793,1533-4406
DOI: 10.1056/nejmoa067597